Weekly Case

Title : case 435

Age / Sex : 42 / F



Chief complaint: palpable mass

What is your impression?

Two weeks later, you can see the final diagnosis with a brief discussion of this case.

(Please submit only one answer)


 


 


 


Courtesy: Hee Jin Park, Kangbuk Samsung hospital


Diagnosis:

Bizarre parosteal osteochondromatous proliferation (BPOP) or Nora's lesion



Discussion


 

- Rare, benign lesion that was first described by Nora et al. in 1983 in the hands or feet of young adults.


- Short tubular bone involvement


- Minor trauma is an etiologic factor in the development of BPOP.


- Antecedent trauma is reported in the patient's history from 0% to 50% of cases.


- Myositis ossificans and florid reactive periostitis may progress to BPOP.


- High recurrence rate after surgical resection, up to 55% of cases


- Histologically it is composed of cartilage, bone and spindle cells. The cartilage may form a cap on the surface of the lesion, and undergoes enchondral ossification. As myositis osfficians does, with time it progresses to mature bone


This benign lesion of the bone might be mistaken for malignant processes because of the high frequency of recurrence, the occasional quick growth and atypical histologic appearance.


* Radiographic findings


- Dense, non-homogeneous and often multilobulated mass with a broad base attached to the bone cortex.


- Heavy mineralization with sclerotic appearance.


- Occasionaly, rapid growth and aggressive features on imaging studies.


- No cortical or permeative bone destruction.


- No continuity between mass and medullary cavity of underlying bone.


- Positive scintigraphy with an intense tracer uptake in the lesion.


 


* MRI features


- Useful in differentiating BPOP from several of its mimickers.


- Low signal on T1WI, high signal on STIR imaging.


- Variable signal on FSE T2 and GRE sequences, probably related to the relative amounts of cartilage present within the lesion.



Correct Answer
Name Institution
이름:소속병원
Total Applicants: 28
Correct answers:14
양지연:오병원
이택기:인하대병원
송윤아:한양대학교 서울병원
이다비:단국대병원
강건우:군의관
최마리아:예병원
김동환:분당제생병원
이혜란:석병원
이승민:단국대병원
이승훈:한양대병원
전성희:중앙보훈병원
이승현:세브란스병원
이보람:아주대학교병원
구혜수:강동경희대병원

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