Age / Sex : 23 / F

Chief complaint : Generalized weakness, loss of appetite, and weight loss


What is your diagnosis?

Two weeks later, you can see the final diagonosis with a brief discussion of this case (Please submit only one answer)

Courtesy : 김현수 (Hyun Su Kim), 삼성서울병원 (Samsung medical center)

Serous atrophy of bone marrow (gelatinous transformation of bone marrow)

Discussion

Findings
Diffuse hypointense signal on T1-weighted and hyperintense signal on T2 fat-suppressed images of the bone marrow and subcutaneous fat.

References
1. Vande Berg B, Malghem J, Devuyst O, Maldague B, Lambert M. Anorexia Nervosa: Correlation Between MR Appearance of Bone Marrow and Severity of Disease. Radiology. 1994;193(3):859-64.
2. DiVasta A, Mulkern R, Gordon C, Ecklund K. MR Imaging in a Case of Severe Anorexia Nervosa: The 'Flip-Flop' Effect. Pediatr Radiol. 2015;45(4):617-20.
3. Ecklund K, Vajapeyam S, Feldman H et al. Bone Marrow Changes in Adolescent Girls with Anorexia Nervosa. J Bone Miner Res. 2010;25(2):298-304.
4. Boutin R, White L, Laor T et al. MRI Findings of Serous Atrophy of Bone Marrow and Associated Complications. Eur Radiol. 2015;25(9):2771-8.