Weekly Case

Title : Case 27

Age / Sex : 16 / M


Age/Sex: 16/M

C.C.: Lt. foot pain (1YA)




1) What is your impression?

Courtesy : Sung Hwan Hong, MD., Seoul National University Hospital


Diagnosis:

osteoid osteoma in the calcaneus



Discussion


Findings:
 - Lateral ankle radiograph shows a radiolucent nidus with central calcification and surrounding sclerosis.
- Sagittal MR images show a subcortical nidus in the calcaneal sulcus. The nidus has a central calcification and is surrounded by sclerotic bone and extensive bone marrow edema in the calcaneus. Soft tissue edema is seen in the tarsal sinus and the planatar side of the calcaneus. Joint effusion and synovial hypertrophy are prominent in the posterior recess of the talocalcaneal joint.

Differential Diagnosis:
osteoid osteoma/ osteomyelitis/ stress fracture Diagnosis: osteoid osteoma in the calcaneus

Discussion:
Osteoid osteoma occurring in the foot is unusual and accounts for approximately 4% of cases. The most common site in the bone of the foot is the talus. The preoperative diagnosis of osteoid osteoma occurring in the foot may be delayed because of unusual location and atypical symptoms. On MRI, the nidus of osteoid osteoma shows low or intermediate signal intensity on spin echo T1-weighted images, variable signal intensity on T2-weighted images, and variable enhancement. Intra-articular lesions cause synovial thickening or inflammation and joint effusion, which may be readily apparent on MRIs. MRI may be misleading because of bone marrow and soft tissue changes associated with osteoid osteoma, which may sometimes be extensive. The misleading appearance of osteoid osteoma on MRI often leads to the diagnosis of osteomyelitis, stress fracture, inflammatory arthritis, or a more aggressive bone tumor. The mechanism that results in bone marrow and soft tissue edema is uncertain; however, prostaglandin, which is reported to be a cause of peritumoral edema on MRI, has been implicated because levels of this inflammatory mediator are elevated in osteoid osteoma.
References:
1. Lee GK, Kang IW, Lee ES, Min SJ, Cho SW, Hwang DH. Osteoid osteoma of the tarsal cuboid mimicking osteomyelitis. AJR 2004;183:341-342
2. Kransdorf MJ, Stull MA, Gilkey FW, Moser RP Jr. Osteoid osteoma. RadioGraphics 1991;11:671 -696 3
. Woods ER, Martel W, Mandell SH, Crabbe JP. Reactive soft-tissue mass associated with osteoid osteoma: correlation of MR imaging features with pathologic findings. Radiology 1993;186:221-225
4. Ehara S, Rosenthal DI, Aoki J, et al. Peritumoral edema in osteoid osteoma on magnetic resonance imaging. Skeletal Radiol1999;28:265-270
5. Yamamura S, Sato K, Sugiura H, et al. Prostaglandin levels of primary bone tumor tissues correlate with peritumoral edema demonstrated by magnetic resonance imaging. Cancer 1997;79:255-261



Correct Answer
Name Institution
서진석 (정답) : 신촌세브란스병원
성미숙 (정답) : 가톨릭의대 성가병원
이민희 (정답) : 강북 삼성병원
김완태 (정답) : 서울 보훈병원
김성준 (정답) : 한양대 구리병원
오배근 (정답) : 일산백병원 전공의
박소영 (정답) : 경희의료원 전공의
양희선 (정답) : 전남대학교병원 전공의

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